Child safety, anti-fever, selected drugs have know-how

In recent days, the fever began to grown children. Anti-fever medicine, I am afraid that most of the family standing is one of the drugs, then the safest kind of anti-fever drugs? How to use it?
Acetaminophen (also known as paracetamol) trade names are: Tylenol,咛100, Angaur hot.
10 kg to 15 mg / time, although anti-fever effect quickly, but control the time the body temperature must be short compared with other drugs, the average control time for about two hours. Its side effects are relatively small, it is safe. At present, widely used around the world, clinical, and children under the age of 2 are used to the drug.

But bearing in mind that the drug has a clear dose-dependent, that is, an increase in efficacy with the dose increased, so to prevent excessive application of the drug caused liver damage.
Ibuprofen trade names are: Merrill Lynch, Tian Qian, Chen Yan-gong, etc. again. Drug and acetaminophen are recommended by the World Health Organization to the children of two antipyretics. Usage: oral 5 ~ 10mg / kg body weight times, 6 to 8 hours 1.
Characteristics: a stable and lasting fever, fever of up to eight hours duration. And its heat (39OC and above) than the anti-fever acetaminophen strong, lasted for a long time.
The main side effects: Mild gastrointestinal reactions, transaminase increased, dual function can affect blood coagulation. Excessive use may inhibit the central nervous system, such as epileptic seizures. Therefore, the drug clinically used for more than 3-year-old children with high fever.
Nimesulide in Italy in 1985 and successfully developed a new type of listing non-steroidal anti-inflammatory, analgesic, antipyretic drug. At present, sales of China's market. Although there will be reported in the literature of nimesulide and ibuprofen were compared, highlighting the advantages of the digestive system is less adverse reactions, but an increasing number of applications reported in the literature that nimesulide has caused severe cases of liver damage.
Aspirin in clinical practice has been not used for anti-fever treatment, only for some special diseases such as Kawasaki disease and so on. Since the 20th century, 70 years, medical scientists found that children with the drug can cause Reye syndrome.
Analgin because of its obvious adverse reactions, which was less used. However, some clinics are still small children, and parents to pay attention to.
The drug is a compound with aspirin lysine salt, can be used for intravenous and intramuscular injection, quick onset, efficacy, and oral and avoid aspirin and ibuprofen on the gastrointestinal tract irritation. Antipyretic effect of the drug, and take effect rapidly, the role of relaxation and long-lasting and less side effects, can be used as a common pediatric antipyretic drugs. However, long-term application may trigger Reye syndrome, and some can induce anaphylactic shock and severe asthma attack.
Usually, when children temperature above 38. 5OC, the doctors suggested that anti-fever drugs, because a fever is the body's defense response, the appropriate human body heat can help to eradicate the virus and bacteria. In addition, care should be taken to deal with anti-fever is only symptomatic treatment based on the cause of anti-fever drug use is relatively safe.